ホワイト.png
PEP.jpg

PEP -X-Y

　　　　　ペプチド　マイクロダイアリシス​　プローブ

​

PEP(AtmosLM)プローブには1,000,000 Da MWCO (分画分子量)の膜があり

巨大分子が通過可能です。プローブ内のベントがプローブ内の気圧の高まり

および大孔膜からの液体の漏れを防ぎます。これまで数多くのタンパク質の

検出に成功しています。これらにはTNF-α、amyloid-ß、IL-6、Tau、BDNF、

CRFが含まれます。マイクロダイアリシスサンプルをプローブから回収する

には、注入用のシリンジポンプに加えて弊社のローラーポンプERP-10が必要

です。

​

Membrane material polyethylene. 0.44 mm OD.
Shaft: 0.58 mm OD/0.5 mm ID

​

AtmosLM　特設ページはこちら

Atmos.png

​＞＞プローブについて

​関連した文献

2020
Collagenous Alzheimer amyloid plaque component impacts on the compaction of amyloid-β plaques

α2-Antiplasmin as a potential regulator of the spatial memory process and age-related cognitive decline

Blockade of the renin-angiotensin system suppresses hydroxyl radical production in the rat striatum during carbon monoxide poisoning

2019​
Late agingeassociated increases in L-DOPAeinduced dyskinesia　are accompanied by heightened neuroinflammation in the hemi-parkinsonian rat

In vivo measurement of enhanced agouti-related peptide release in the paraventricular nucleus of the hypothalamus through Gs activation of agouti-related peptide neurons

Frequency-dependent exacerbation of Alzheimer’s disease neuropathophysiology

Assessment of extracellular cytokines in the hippocampus of the awake behaving rat using large-molecule microdialysis combined with multiplex arrays after acute and chronic ethanol exposure.

2016
Seed-competent HMW tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients

2015
Oxidative stress and lipid peroxidation are upstream of amyloid pathology

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain

Improvement of memory deficits and Aβ clearance in aged APP23 mice treated with a combination of anti-Aβ antibody and LXR agonist

2014
A Food and Drug Administration-approved Asthma Therapeutic Agent Impacts Amyloid  in the Brain in a Transgenic Model of Alzheimer Disease

Involvement of substance P in the development of cisplatin-induced acute and delayed pica in rats

2013
Brain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease

Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain