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All-In-One HPLC

> Trouble-free integrated system

> Maximum sensitivity every day

> Minimal lag from start to stable

> Simple to operate and maintain

The HTEC-510 is the world's only complete stand alone HPLC-ECD system.

It was designed with simplicity in mind. The integrated design stabilizes

quickly and provides excellent sensitivity. All the components, Pump,

degasser, detector, and temperature control, fit neatly into one compact

cabinet. The innovative pulse quenching pump eliminates the need for a 

pulse damper. This system is sure to impress both expert and novice alike.

Get results fast with ready-to-use applications.

> Trouble-free integrated system

> Maximum sensitivity every day

> Minimal lag from start to stable

> Simple to operate and maintain


Up to 4 animals can be sampled simultaneously



しかし、ダンパーには10 ml程度の内容量があり、この容量が






そして、ポンプを4 µL/ストロークと小容量のバイナリーピスト


そのため、ポンプピストンからカラムまでの容量が1 ml以下と




Tissue/blood/other samples

​方     式: パルスフリーレスプロ型

接液部、材 質: PEEK、フッ素樹脂による完全メタルフリー

・Membrane material is regenerated cellulose molecular weight cutoff value 50000 (Da)

流 量 設 定: 液晶表示による1μL/minステップ

耐     圧: 20Mpa




方     式: アンペロメトリック

加電圧  範囲: 0~±1990mV

作用電極種類 : グラファイト、ピュアグラファイト


作 用 電 極: 薄層・ワンタッチ交換方式

​参 照 電 極: 銀 / 塩化銀 


方     式: ペルチェ素子による

温度設定範囲 : 20~45℃

重     量:    18kg

寸     法: 250(W) x 370(D) x 390(H) mm

​電     源: AC100V



  • 超高感度

  • 高安定

  • メンテナンスの必要性が最小限であるため、稼働率が非常に高い

  • 小型、省スペース

  • ひとつのディスプレーからの直感的操作性

  • 予期せぬトラブルを防止する、イナート仕様

  • パワフルなアプリケーション.

  • 信頼の置けるサポート 


> エラー4対処方法


Mobile Phase setting

Electrodes & Columns setting

Common HPLC pumps are not suitable for electrochemical detectors.
Glucose infusion suppresses acute restraint stress-induced peripheral and central sympathetic responses in rats

Investigating the Influence of GABA Neurons on Dopamine Neurons in the Ventral Tegmental Area Using Optogenetic Techniques

The efficacy of duloxetine depends on spinal cholinergic plasticity in neuropathic pain model rats

Behavioral and neurochemical effects of novel N-Benzyl-2-phenylethylamine derivatives in adult zebrafish

Spike firing attenuation of serotonin neurons in learned helplessness rats is reversed by ketamine

l-Menthol increases extracellular dopamine and c-Fos-like immunoreactivity in the dorsal striatum, and promotes ambulatory activity in mice

P2X2 receptors supply extracellular choline as a substrate for acetylcholine synthesis

Reduction of acetylcholine in the hippocampus of hippocampal cholinergic neurostimulating peptide precursor protein knockout mice

The essential role of transcription factor Pitx3 in preventing mesodiencephalic dopaminergic neurodegeneration and maintaining neuronal subtype identities during aging

Ninjin'yoeito, a traditional Japanese medicine, increases dopamine content in PC12 cells

Preventative Effects of 1-Methyl-1,2,3,4- Tetrahydroisoquinoline Derivatives (N-Functional Group Loading) On MPTP-Induced Parkinsonism In

Simultaneous serotonin and dopamine monitoring across timescales by rapid pulse voltammetry with partial least squares regression

A novel in vitro assay model developed to measure both extracellular and intracellular acetylcholine levels for screening cholinergic agents

Hormonal and Neurological Aspects of Dog Walking for Dog Owners and Pet Dogs

Ninjin’yoeito, a traditional Japanese medicine, increases dopamine content in PC12 cells

FFAR1/GPR40 Contributes to the Regulation of Striatal Monoamine Releases and Facilitation of Cocaine-Induced Locomotor Activity
in Mice

α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability

Modulation of behavioral and neurochemical responses of adult zebrafish by fluoxetine, eicosapentaenoic acid and lipopolysaccharide in the prolonged chronic unpredictable stress model

Genetic dissection identifies Necdin as a driver gene in a mouse model of paternal 15q duplications

Schizophrenia-Like Behavioral Impairments in Mice with Suppressed Expression of Piccolo in the Medial Prefrontal Cortex

Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment

In Vivo Monitoring of Acetylcholine Release from Nerve Endings in Salivary Gland

The Effects of Acute Glucoprivation on Adrenomedullary Function in SHR and WKY Rats

Mice with mutations in Trpm1, a gene in the locus of 15q13.3 microdeletion syndrome, display pronounced hyperactivity and decreased anxiety-like behavior

Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications

Dual actions of 5-MeO-DIPT at the serotonin transporter and serotonin 5-HT1A receptor in the mouse striatum and prefrontal cortex

Decreased content of ascorbic acid (vitamin C) in the brain of knockout mouse models of Na+,K+-ATPase-related neurologic disorders

Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration

Non-neuronal cardiac acetylcholine system playing indispensable roles in cardiac homeostasis confers resiliency to the heart

Beta-blockade Prevents Coronary Macro and Microvascular Dysfunction Induced by a High Salt Diet and Insulin Resistance in the Goto-Kakizaki Rat

Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex

Mice with Mutations in Trpm1, a Gene within the locus of 15q13.3 Microdeletion Syndrome, Display Pronounced Hyperactivity
and Decreased AnxietyLike Behavior.

Understanding complex dynamics of behavioral, neurochemical and transcriptomic changes induced by prolonged chronic unpredictable stress in zebrafish

Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons

Noradrenaline enhances the excitatory effects of dopamine on medial prefrontal cortex pyramidal neurons in rats

Absence of methamphetamine‐induced conditioned place preference in weaver mutant mice

Monoamine and genome-wide DNA methylation investigation in behavioral addiction

Highly Efficient Conversion of Motor Neuron-Like NSC-34 Cells into Functional Motor Neurons by Prostaglandin E2

Monoamine and genome-wide DNA methylation investigation in behavioral addiction

Gamma oryzanol impairs alcohol-induced anxiety-like behavior in mice via upregulation of central monoamines associated with Bdnf and Il-1β signaling

Participation of the nucleus accumbens dopaminergic system in the antidepressant-like actions of a diet rich in omega-3 polyunsaturated fatty acids

Early weaning augments the spontaneous release of dopamine in the amygdala but not the prefrontal cortex: An in vivo microdialysis study of male rats

VGLUT2-expressing neurons in the vestibular nuclear complex mediate gravitational stress-induced hypothermia in mice

Brain Angiopathy and Impaired Glucose Metabolism in Model Mice with Psychiatric-Related Phenotypes

Tyr-Trp administration facilitates brain norepinephrine metabolism and ameliorates a short-term memory deficit in a mouse model of Alzheimer's disease

Twelve-Month Studies on Perilla Oil Intake in Japanese Adults—Possible Supplement for Mental Health​

The Effect of Stressor Controllability on Social Hedonic Preference in Laboratory Rats

Gamma Oryzanol Alleviates High-Fat Diet-Induced Anxiety-Like Behaviors Through Downregulation of Dopamine and Inflammation in the Amygdala of Mice

Direct visualization of an antidepressant analog using surface-enhanced Raman scattering in the brain

Prolyl-hydroxyproline, a collagen-derived dipeptide, enhances hippocampal cell proliferation, which leads to antidepressant-like
effects in mice

Protein Deficiency-Induced Behavioral Abnormalities and Neurotransmitter Loss in Aged Mice Are Ameliorated by Essential Amino Acids

Angiopathy with impaired glucose logistics observed in schizophrenia-like model mice

Trace Amine-Associated Receptor 5 Provides Olfactory Input Into Limbic Brain Areas and Modulates Emotional Behaviors and Serotonin Transmission

Activation of mGluR5 and NMDA Receptor Pathways in the Rostral Ventrolateral Medulla as a Central Mechanism for Methamphetamine-Induced Pressor Effect in Rats

(R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent

Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain

Parkinson's disease recovery by GM1 oligosaccharide treatment in the B4galnt1+/- mouse model

Hyperreflexia induced by XLR-11 smoke is caused by the pyrolytic degradant

Thiamine tetrahydrofurfuryl disulfide promotes voluntary activity through dopaminergic activation in the medial prefrontal cortex

Effects of Memantine on Nitric Oxide Production and Hydroxyl Radical Metabolism during Cerebral Ischemia and Reperfusion in Mice

Overexpression of transmembrane protein 168 in the mouse nucleus accumbens induces anxiety and sensorimotor gating deficit

Prenatal nicotine exposure decreases the release of dopamine in the medial frontal cortex and induces atomoxetine-responsive neurobehavioral deficits in mice

The Role of Spinal Dopaminergic Transmission in the Analgesic Effect of Nefopam on Rat Inflammatory Pain

Abuse-Related Neurochemical Effects of Para-Substituted Methcathinone Analogs in Rats: Microdialysis Studies of Nucleus Accumbens Dopamine and Serotonin

Novel psychoactive benzofurans strongly increase extracellular serotonin level in mouse corpus striatum

Sex Differences in Abuse-Related Neurochemical and Behavioral Effects of 3,4-methylenedioxymethamphetamine (MDMA) in Rats

Brain regions and monoaminergic neurotransmitters that are involved in mouse ambulatory activity promoted by bupropion

Injection of corticotropin-releasing hormone into the amygdala aggravates visceral nociception and induces noradrenaline release in rats

Pregerminated Brown Rice Enhanced NMDA Receptor/CaMKIIα Signaling in the Frontal Cortex of Mice 
Monitoring Serotonin: Why Faster is Better

Physiologically Relevant Changes in Serotonin Resolved by Fast Microdialysis

Pain-Related Depression of the Mesolimbic Dopamine System in Rats: Expression, Blockade by Analgesics, and Role of Endogenous κ-opioids

Symmetrical Serotonin Release during Asymmetrical Slow-Wave Sleep: Implications for the Neurochemistry of Sleep–Waking States

Oral administration of glycine increases extracellular serotonin but not dopamine in the prefrontal cortex of rats

GABAergic transmission in the rat ventral pallidum mediates a saccharin palatability shift in conditioned taste aversion

Cortical Acetylcholine Release Is Lateralized during Asymmetrical Slow-Wave Sleep in Northern Fur Seals

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